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IC‐P‐129: Regional Brain Aerobic Glycolysis Across The Cognitively Normal Adult Life Span
Author(s) -
Vlassenko Andrei G.
Publication year - 2016
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2016.06.159
Subject(s) - cerebral blood flow , positron emission tomography , brain aging , neuroprotection , human brain , cognitive decline , anaerobic glycolysis , medicine , aging brain , psychology , disease , glycolysis , dementia , neuroscience , physiology , pathology , endocrinology , metabolism
thicknesses. Siemens Healthcare MRIs had very similar fitted curves for surface, thickness, and volume, while Philips Medical Systems MRIs had thickness curves with a wider discrepancy, albeit surfaces and volumes were similar. Conclusions: OEMs andMFS produce small, but non-negligible effects on cortical surfaces, thicknesses, and volumes. These effects need to be taken into account when designing multi-centric studies and/or making between-scanner comparisons.