Premium
P2‐315: VISUO CONSTRUCTIVE EVALUATION IN MILD COGNITIVE IMPAIRMENT AND ALZHEIMER'S DISEASE
Author(s) -
San Pedro Caligua Rafael Oscar,
Sosa-Ortiz Ana Luisa
Publication year - 2016
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2016.06.1445
Subject(s) - audiology , cognitive impairment , dementia , neuropsychology , psychology , medicine , test (biology) , mann–whitney u test , cognition , disease , clinical psychology , psychiatry , paleontology , biology
scales is thus an important clinical and research issue. The Everyday Cognition (ECog) scale is a relatively new informant and subjective-rated measure of cognitive and instrumental activities of daily living everyday function. The objective of this study was to determine validity and internal consistency of the informant-rated ECog scale in the Argentina-Alzheimer’s Disease Neuroimaging Initiative (Arg-ADNI) sample. Methods:We evaluated 15 clinically normal elderly (CN), 28 mild cognitive impairment (MCI), and 13 mild Alzheimer’s Disease (AD) dementia subjects from Arg-ADNI. External, convergent and divergent validity and internal consistency were examined. Results:The average total score on the ECog scale was significantly different across the three diagnostic syndromes (p<.05). The area under the curve (AUC) for the ECog was .978 (95% CI1⁄4 .94-.99). The ECog scale was more sensitive than Functional Activities Questionnaire (FAQ) in discriminating between normal subjects and MCI patients. The ECog scale showed a moderate to strong correlation with other measures of daily function, including the Clinical Dementia Rating (CDR) and the FAQ scales and moderate correlations with neuropsychological tests. Cronbach’s alpha was .98. Co-varying for age or education had no effect on these results. Conclusions:The ECog scale is an efficient instrument for the differentiation of individuals with mild dementia or MCI from normal older adults, with good accuracy and good correlation with other tests measuring daily and cognitive functions.