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P2‐151: Cerebrospinal Fluid Biomarker Profile of Amyloid, TAU, Synaptic, Microglial, and Lysosomal Pathophysiology in Cognitively Normal Preclinical Individuals Stratified by Amyloid‐Pet Status
Author(s) -
Hampel Harald,
Lista Simone,
Zetterberg Henrik,
Blennow Kaj,
Habert Marie-Odile,
Nyasse Francis,
Bakardjian Hovagim,
Lamari Foudil,
Dubois Bruno
Publication year - 2016
Publication title -
alzheimer's and dementia
Language(s) - Norwegian
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2016.06.1318
Subject(s) - neurogranin , biomarker , cerebrospinal fluid , neurodegeneration , pathology , pathophysiology , medicine , amyloid (mycology) , oncology , disease , chemistry , biochemistry , protein kinase c , enzyme
OFAMYLOID, TAU, SYNAPTIC, MICROGLIAL, AND LYSOSOMAL PATHOPHYSIOLOGY IN COGNITIVELY NORMAL PRECLINICAL INDIVIDUALS STRATIFIED BYAMYLOID-PET STATUS Harald Hampel, Simone Lista, Henrik Zetterberg, Kaj Blennow, Marie-Odile Habert, Francis Nyasse, Hovagim Bakardjian, Foudil Lamari, BrunoDubois, SorbonneUniversites, Universite Pierre et Marie Curie, Paris, France; Sorbonne Universit es, Universit e Pierre et Marie Curie (UPMC), Paris, France; Institute of Neuroscience and Physiology, The Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden; 4 Sorbonne Universites, UPMC Univ Paris 06, Inserm U 1146, CNRS UMR 7371, Laboratoire d’Imagerie Biomedicale, Paris, France; Institut de la M emoire et de la Maladie d’Alzheimer (IM2A), Paris, France; 6 IHU-A-ICM Paris Institute of Translational Neurosciences, Hopital Pitie-Salpetriere, Paris, France; 7 Service de Biochimie M etabolique, Hôpital Piti e-Salpêtri ere, Paris, France; Sorbonne Universite, Universite Pierre et Marie Curie-Paris 6, Paris, France. Contact e-mail: Harald.Hampel@med.uni-muenchen.de