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P1‐377: Association Between Serum Calcium and Cognitive Function in Healthy People Aged 60 or Older in The Vital Study
Author(s) -
Ogata Soshiro,
Mora Samia,
Okereke Olivia I.,
Cook Nancy R.,
Manson JoAnn E.,
Grodstein Francine,
Kang Jae Hee
Publication year - 2016
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2016.06.1129
Subject(s) - quartile , medicine , cognition , vitamin d and neurology , linear regression , calcium , blood pressure , confidence interval , psychiatry , machine learning , computer science
distribution in scoring of cognitive domains in the MoCA than in the MMSE. Mean MoCA total scores showed a declining trend both in lower education and increasing age. Significant correlation was found in all cognitive domains, with Orientation and Attention having a stronger correlation. All t-values reached significance level, with the exception of the drawing domain. The scores in the MoCA test showed both educational and age effects in the total scores of the participants. Our findings show that, two screening tests measure similar cognitive domains, as evident from the significant correlations, it is also apparent that there is a difference to the degree of these measurements. In particular, participants generally performed better in the MMSE than in the MoCA screening test, as the mean total score for MMSE is significantly greater. This can be attributed to the MMSE’s ceiling effect, in which participants tend to perform in the higher range of scores. Moreover, the range of scores in MoCA is much wider – with participants scoring as low as 8 points and as high as 30 points. Conclusions:A minimum of six years of education may produce cognitive reserve in the elderly, Cognitive decline emerge after the age of 60 years old. Cognitive decline in individuals of low education has shown some base effect by the age of 60. Cognitive Public screening and education plays vital role to society to create awareness and detect early the memory problems so that physicians embark preventive strategies at earlier stage.