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P4‐177: An ultrasensitive immunoassay detects soluble Aβ oligomers in tg mice prior to memory loss
Author(s) -
Cline Erika N.,
Viola Kirsten L.,
Rollins Madeline G.,
Mohammad Saad N.,
Zieske Lynn R.,
Klein William L.
Publication year - 2015
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2015.08.005
Subject(s) - immunoassay , antibody , monoclonal antibody , medicine , amyloid β , pathogenesis , biomarker , chemistry , microbiology and biotechnology , disease , biochemistry , immunology , biology
Fig 1. Cross-sectional Effect Size for various FreeSurfer based reference regions. SUVR reference regions included (in decreasing order from from left to right) an average of WMeroded, WC and BS (AvgRef). eroded subcortical white matter (WMeroded). subcortical white matter (WM). thresholded brainstem (BSth). brainstem (BS). whole brain (WB). whole cerebellum (WC). cerebellar white matter (WTvIcerebellum). and cerebellar grey (CG). The AvgRef Freesurfer method yielded the highest effect size (Coheir sD of 3.883).