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F4‐02‐04: The influence of multimorbidity on clinical progression of dementia in a population‐based cohort
Author(s) -
Melis René J.F.,
Marengoni Alessandra,
Rizzuto Debora,
Kivipelto Miia,
Angleman Sara,
Fratiglioni Laura
Publication year - 2015
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2015.07.336
Subject(s) - dementia , cohort , activities of daily living , cognitive decline , medicine , population , cohort study , gerontology , cognition , psychiatry , disease , environmental health
verbal fluency (beta1⁄4-0.16, p<0.01), while patients with mild or no comorbidity remained generally stable. However, severity of comorbidity was not associated with a higher risk of conversion to dementia within three years. Conclusions: The severity of total comorbidity is associated with lower performance and faster decline on mental speed dependent tests, and should thus be taken into account when evaluating cognitive performance in clinical practice. However, severity of comorbidity is not associated with a higher risk of conversion to dementia.