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O3‐10‐01: Neuropsychological markers of cognitive decline in persons with Alzheimer's disease neuropathology
Author(s) -
Monsell Sarah E.,
Hassenstab Jason,
Mock Charles,
Roe Catherine M.,
Cairns Nigel J.,
Morris John C.,
Kukull Walter
Publication year - 2015
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2015.07.291
Subject(s) - neuropathology , episodic memory , neuropsychology , cognition , clinical dementia rating , dementia , effects of sleep deprivation on cognitive performance , psychology , alzheimer's disease , cognitive decline , medicine , disease , psychiatry , cognitive impairment
level and right hippocampal volume) were associated with distinct subtypes of either the motor (mot), attentional (att) or posterior cingulate (pcc) networks. Difference stability maps reveal how subtypes differ from the grand mean maps, (b) Two associations were robust after FDR correction across networks and subtypes (q<0.05). Six associations were identified for further exploration at q<0.2. A similar analysis on an independent retest run in the same subjects showed trends (p<0.1) for 5 out of the 8 associations. Podium Presentations: Tuesday, July 21, 2015 P240