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O2‐12‐05: Isoform‐specific rcan1 overexpression promotes age‐dependent mitochondrial dysregulation related to neurodegeneration in Alzheimer's disease
Author(s) -
Hoeffer Charles A.,
Wong Helen,
Levenga Josien G.,
Cain Peter,
Klann Eric,
Rothermel Beverly
Publication year - 2015
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2015.07.199
Subject(s) - neurodegeneration , biology , neuroscience , phenotype , gene isoform , hyperphosphorylation , mitochondrion , oxidative stress , microbiology and biotechnology , disease , medicine , endocrinology , kinase , genetics , gene
O2-12-05 ISOFORM-SPECIFIC RCAN1 OVEREXPRESSION PROMOTES AGE-DEPENDENTMITOCHONDRIAL DYSREGULATION RELATED TO NEURODEGENERATION IN ALZHEIMER’S DISEASE Charles A. Hoeffer, Jr., Helen Wong, Josien G. Levenga, Peter Cain, Eric Klann, Beverly Rothermel, University of Colorado, Boulder, Boulder, CO, USA; Institute for Behavioral Genetics, Boulder, CO, USA; New York University, New York, NY, USA; University of Texas, Southwestern, Dallas, TX, USA. Contact e-mail: charles.hoeffer@colorado. edu