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O1‐10‐01: Estimating effect size of APOE genotype on Alzheimer's disease progression to determine the likely impact on clinical trial design
Author(s) -
Feng Sheng
Publication year - 2015
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2015.07.081
Subject(s) - apolipoprotein e , population , clinical trial , cognitive decline , sample size determination , disease , allele , genotype , medicine , psychology , gerontology , oncology , dementia , biology , genetics , gene , statistics , mathematics , environmental health
The prevalence of MI, PD and CI among Chinese elderly in communities were deceasing during the last decade, consistence to existing literatures, with variation between male and female, urban/ rural residence and age groups. The decline in the three indexes over time was partly attributed to the confounding of age effects. Other possible factors associated the decline in prevalence are under investigation.