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P2‐160: 31 P magnetic resonance spectroscopy on normal aging human brain at 3.0T
Author(s) -
Chiu Pui Wai,
Chi Andrew,
Law Kin,
Shiu Joseph,
Kwan Kwong,
Chuen Raymond,
Chang Chung,
Chu Leung Wing,
Fung Mak Henry Ka
Publication year - 2015
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2015.06.699
Subject(s) - phosphocreatine , nuclear magnetic resonance , voxel , nuclear medicine , in vivo magnetic resonance spectroscopy , magnetic resonance imaging , nuclear magnetic resonance spectroscopy , flip angle , metabolite , alzheimer's disease neuroimaging initiative , hippocampus , correlation , posterior cingulate , chemistry , medicine , alzheimer's disease , mathematics , physics , functional magnetic resonance imaging , radiology , energy metabolism , geometry , disease
patients with confirmed diagnosis of AD (11.8% increase V1⁄449, p<.05; Figure 2) and those with confirmed diagnosis of non-AD (13.6% increase; V1⁄40, p<.05; Figure 3). 243 PET scans were evaluated by two nuclear medicine physicians, who disagreed on 32 cases (rate of concordance: 86.8%). Conclusions:Data are in line with previous reports. Based on preliminary results, amyloid PET with 18F-Florbetapir has a significant impact on diagnosis and diagnostic confidence of dementia experts.