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P2‐094: Can cognitive deficits predict remission in late life depression disorder?
Author(s) -
Avila Renata,
Imanari Ribeiz Salma Rose,
Zucolo Pedro,
Jaluul Omar,
Campos Bottino Cassio M.
Publication year - 2015
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2015.06.631
Subject(s) - cognition , depression (economics) , neuropsychology , executive dysfunction , executive functions , psychology , psychiatry , clinical psychology , major depressive disorder , medicine , economics , macroeconomics
participants were prevented from viewing the start point from any point by carefully chosen locations. The angle deviation from the correct response at each point was recorded and analyzed. Results:The angle deviation showed difference among three groups at point 3 (p1⁄40.017), point 4 (p1⁄40.000) and point 5 (p1⁄40.000). Post hoc analysis showed that the performance of PI differentiates AD from non-AD at point 4 and point 5. It also showed that the angle deviations at point 4 are correlated with all components of the QuENA, namely landmark agnosia, egocentric disorientation, heading disorientation and inattention, while that at point 5 with components of landmark agnosia and heading disorientation. No correlation was found between the perfusion deficit and angle deviation at any point. Conclusions: The relationship between the brain dysfunction and the performance of PI is more complex as previously thought. More in-depth design and careful interpretation are in need to develop a new tool for helping diagnosis of the MCI and monitoring the progress of AD.