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P1‐264: The role of sex in postoperative cognitive and functional decline
Author(s) -
Schenning Katie J.,
Murchison Charles F.,
Mattek Nora,
Kaye Jeffrey,
Quinn Joseph F.
Publication year - 2015
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2015.06.465
Subject(s) - neurocognitive , cognitive decline , clinical dementia rating , medicine , cognition , dementia , ageing , activities of daily living , cohort , natural history , gerontology , disease , physical therapy , psychiatry
unchanged after further adjustment for a large set of lifestyle, vascular and cognitive factors. In contrast, we found no relation with grey matter volumes. Conclusions: The MeDi appears to benefit brain health through preservation of structural connectivity. The strong relation of theMeDi with white matter microstructure in extensive areas with no substantial association with grey matter volumes suggests that the MeDi may benefit the brain through a favorable impact on cerebral vasculature; mediation by early vascular mechanisms deserves further research.