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P1‐242: Executive function moderates the relationship between physical performance and functional independence in older adults
Author(s) -
Dickens Jonathan M.,
Mewborn Catherine,
Lindbergh Cutter A.,
Sharma Shubam,
Stapley Leslie,
Goldy Sean,
Renzi Lisa M.,
Hammond Billy R.,
Miller L. Stephen
Publication year - 2015
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2015.06.442
Subject(s) - moderation , clinical dementia rating , psychology , balance (ability) , independence (probability theory) , gerontology , physical therapy , physical medicine and rehabilitation , medicine , cognition , cognitive impairment , social psychology , psychiatry , statistics , mathematics
We translated the test “partial knowledge of abstract words” into Thai and investigated the occurrence of partial knowledge effects in the conceptual domain of abstract words in individuals with frontotemporal dementia-semantic dementia (FTD-SD), Alzheimer disease (AD), and other dementia. Twelve FTD-SD, 14 AD, 7 non-amnestic mild cognitive impairment (non-am MCI), 3 other dementia, and 10 healthy controls were examined with 3 level synonym comprehension abstract word test. They include antonym distractors, distant distractors, and close distractors. Results: Mean scores of the antonym distractors, distant distractors, and close distractors of dementia groups and controls were displayed in figure 1. All dementia groups showed weaker performance on choosing distant distractors and close distractors, which requires a fine specification of word meaning, than controls. The impairment of partial knowledge of abstract words was greater in those with SD than AD compared to controls (SD: antonym distractor SE1⁄43.43 p1⁄40.034, distant distractors SE1⁄43.36, p1⁄40.001, close distractor SE 1⁄42.69, p1⁄40.002; AD: antonym distractor SE1⁄43.31, p1⁄40.03, distant distractors SE1⁄43.25, p1⁄40.005, close distractor SE1⁄42.6, p1⁄40.016). We found that 3 subjects with Parkinson dementia and vascular dementia performed worst. However, the number of subjects in this group was small. Conclusions: These findings demonstrate that a degraded conceptual knowledge of abstract words is a phenomenon in neurodegenerative diseases and vascular dementia. Detailed information of abstract words is more affected than broad-sense information.