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P1‐148: Smart‐sport and cerebral metabolism in old age: An mrs/MRI study
Author(s) -
Matura Silke,
Tesky Valentina A.,
Pilatus Ulrich,
Hattingen Elke,
Fleckenstein Johannes,
Vogt Lutz,
Banzer Winfried,
Deichmann Ralf,
Lienerth Bianca,
Pantel Johannes
Publication year - 2015
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2015.06.346
Subject(s) - phosphocreatine , creatine , neuropsychology , cognition , physical therapy , medicine , phosphocholine , aerobic exercise , psychology , physical medicine and rehabilitation , psychiatry , energy metabolism , phospholipid , phosphatidylcholine , membrane , biology , genetics
each population separately. Results: Figure 1 shows 12 transverse slices of the average WMH maps for the entire PREVENT-AD and ADC populations overlapped on the ADNI template. Conclusions:WMHs have been observed in normal control subjects at risk of AD as well as NC/MCI/AD population. WMHs occur more often in the periventricular areas especially adjacent to the horns of the lateral ventricles and less often in the other areas. The difference between the two maps suggests that WMHs are more extensive in AD populations than in healthy controls at risk of AD, especially in regions such as parietal lobe suggesting the probability of an inhomogeneous spread of the WMHs in different regions. (Funding: CIHR MOP-111169, P30 AG010129, Pfizer Canada, FRQ-S, and Douglas Hospital Research Centre.)