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P1‐138: Walking ability and cognitive function change in normal pressure hydrocephalus patients after cerebrospinal fluid tap test
Author(s) -
Liu Caiyan,
Gao Jing,
Mao Chenhui,
Cui Liying,
Peng Bin,
Hou Bo,
Feng Feng,
Wei Junji,
Wang Renzhi
Publication year - 2015
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2015.06.336
Subject(s) - medicine , cerebrospinal fluid , spinal tap , corpus callosum , lumbar puncture , stroop effect , normal pressure hydrocephalus , pathology , cognition , dementia , disease , psychiatry
capacity by scale of daily activities. The sample comprised 110 patients with dementia: 74 with Alzheimer’s disease, 12 with vascular dementia diagnosed with Hachinski Ischemia Scale score at least 7 points, plus focal neurological signs, visible lesions on computed tomography, and 24 with other dementias. Results: 6 patients (5.4%) felt that life is not worth living, 3 (2.7%) had wanted to die, one (0.9%) had sinucidal gestures and none made a suicide attempt. The 4 patients who “wanted to die” or had suicidal thoughts had a score of at least 12 on the HAMD. Of these, 3 were clinically depressed. Suicidal ideation and “desire to die” were significantly correlated only with the presence of depressive symptoms in patients with Alzheimer’s disease. There were no significant differences in HAMD scores between groups of dementia. Conclusions:Suicidal ideation and / or “desire to die” was self-reported by 4% of patients with dementia and is associated with co-morbid depressive symptoms, especially in Alzheimer’s disease.