Premium
P1‐134: Neurobehavioral characterization of adult‐onset alexander's disease: A family study
Author(s) -
Lichtenstein Maya L.,
Dwosh Emily,
Roychowdhury Anupama,
Feldman Howard
Publication year - 2015
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2015.06.332
Subject(s) - psychology , perseveration , apathy , sibling , mood , audiology , psychiatry , cognition , developmental psychology , medicine
MiDD was 9.90% in NCD, 16.89% in MCI, and 19.51% in ADD. The frequency of NIMH-dAD was 26.23%, 33.56%, and 40.24%, respectively. While the frequency of MaDD did not show any significant difference among cognitive subgroups, those of MiDD and NIMH-dAD, i.e., relatively milder depression syndromes, had significant group difference with gradual increase from NCD to ADD. Conclusions: The current findings obtained from a large number of cognitively diverse elderly individuals who visited a memory clinic indicated that mild depressive conditions are highly prevalent in general and more common in individuals with poorer cognitive condition, while the frequency of severe depressive disorder like MaDD is not related to cognitive status.