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P4‐145: Gene, exercise, and memory study (GEMS): A randomized controlled clinical trial to evaluate the effects of standardized aerobic exercise on cognition and neurodegeneration in african americans with mild Alzheimer's disease
Author(s) -
Obisesan Thomas O.
Publication year - 2015
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2015.06.1851
Subject(s) - aerobic exercise , randomized controlled trial , physical therapy , medicine , neuropsychology , dementia , clinical dementia rating , cognition , physical medicine and rehabilitation , psychology , disease , psychiatry
Figure. Longitudinal trends in Alzheimer disease severity in the ADNIj (left panel) and BIOCARD (right panel). This figure shows a random sample of longitudinal trajectories for select ADNI (left panel) and BIOCARD (right panel) subgroups. Persons who begin the study in the normal group and do not convert over 48M follow-up are shown with solid blue lines without markers (dots). The average trajectory for this group is shown with a heavy blue dashed line. MCI cases who do not convert to dementia are shown with solid green lines and the average trend line for these cases is shown by the heavy dashed green line. Persons who begin with clinical AD are shown in solid red lines. The trend line for this group is shown with a heavy dashed red line. Persons who convert (either from normal to mild cognitive impairment (MCI) or AD or form MCI to AD are drawn with black lines, and colored dots indicate their current (at time of assessment) clinical stage as indicated in the key. The average trajectory for this group is shown with a solid black line. Values plotted are best unbiased linear predictors based on a linear mixed effect regression model of predicted AD severity score score.