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P4‐142: The sensitivity and specificity of the chinese version of ad8 in a nationwide screening for dementia in taiwan
Author(s) -
Chen Ta-Fu,
Sun Yu,
Chiu Ming-Jang,
Wang Pei-Ning,
Tang Li-Yu,
Lee Huey-Jane
Publication year - 2015
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2015.06.1848
Subject(s) - cronbach's alpha , receiver operating characteristic , dementia , medicine , population , youden's j statistic , clinical psychology , psychometrics , environmental health , disease
Background: To estimate the prevalence and incidence rates of Amnesia mild cognitive impairment (aMCI), Vascular mild cognitive impairment (vMCI), Alzheimer’s disease (AD), Vascular dementia (VD), mixed dementia (MD), sub-clinical depression (SCD), depressive disorder (DD) and successful aging (SA) in the elderly in Shanghai communities. Methods: In this one-year longitudinal survey, a target group of 1,302 individuals aged over 60 years old was randomly selected from each of three candidate communities. Two diagnostic methods were used to determine depression disorder and cognitive impairments and successful aging: clinical assessments and/or sections of the Structured Clinical Interview for DSM. Prevalence were determined by dividing the total number of cases diagnosed at the baseline visit by the total number of participants (expressed as percentages). Incidence rates are expressed as the number of cases per 1,000 person-years. Results: The total prevalence of psychological and cognitive impairment in those above 60 years of age were: aMCI 22.3%, vMCI 4.1%, AD 4.8%, VD 2.4%, mixed dementia 1.3%, other dementia 2.9%, SCD 1.3%, DD 0.6%, and SA 3.5%. The incidence rates of per 1,000 person-years were: aMCI 102.11, vMCI 21.13, AD 21.13, VD 10.56, SCD 3.52, DD 7.04, total 165.49. aMCI conversion rates were: aMCI non-conversion 55.0%, vMCI 2.7%, AD 11.7%, VD 1.8%, normal aging 26.1%, DD 1.8%, and others 0.9% in one year. Conclusions:The present study indicates that depression and dementia are a considerable health problem. Special attention should be given to developing strategies to postpone or even prevent the development of new cases of depression and dementia.