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P3‐247: Validation study of the mini‐mental state examination in the urdu language for a pakistani population
Author(s) -
Awan Safia
Publication year - 2015
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2015.06.1619
Subject(s) - dementia , urdu , medicine , cutoff , population , demography , disease , linguistics , philosophy , physics , environmental health , quantum mechanics , sociology
with CI secondary to FND and NDwere enrolled in an outpatient CIT program (n1⁄4219). The samplewas divided into 2 groups: patients that received NRD (n1⁄485) (G1), and patients that did not receive NRD (n1⁄4134) (G2). The groupswere paired by age, education,MiniMental StateExamination,Beck Inventory (BI), timeof progression, andnumber of sessions. Cognitive variables, behavioral variables, Activities of DailyLiving (ADL) andQuality of Life (QoL)were compared at treatment start and treatment end. Parametric statistics and analysis were performed at paired samples. Results: Drug-use rates were as follows: 37% antiplatelet aggregating agents, 32.9% antidepressant agents; 21% cholinesterase inhibitors (60.9% donezepil), 22.4% antiepileptic agents, 20.1% antipsychotic agents (60.5% quetiapine), and 17.4% memantine. Regarding NRD: 32.9% (n1⁄472/219) received benzodiazepines, 4.6%(n1⁄410/219) anticholinergic agents, and2.28%(n1⁄45/219) were administered barbiturates. At CIT end, G1 only evidenced improved QoL (mean change (MCh)1⁄44.78;p:0.01). G2 exhibited improved Subjective Memory (MCh1⁄45.74;p:0.03), basic ADL (MCh1⁄41.4;p:0.009) and instrumental ADL (MCh1⁄41.08;p:0.01), BI (MCh1⁄41.9;p:0.01), and Neuropsychiatric Inventory (MCh1⁄46.12; p:0.01).Conclusions: Asignificant number of patientswithCI received NRD. CIT led to significant improvement at some of the study variables, with a lower effect on patients who received drugs with prejudicial effects on cognition.