Premium
P3‐233: Effects of dietary n‐3 pufa intervention on cognitive function and mental health in japanese oldest‐elderly with dementia
Author(s) -
Kato Setsushi,
Hashimoto Michio,
Ohno Miho,
Kato Kyoko,
Katakura Masanori,
Tanabe Yoko,
Yamaguchi Shuhei,
Shido Osamu
Publication year - 2015
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2015.06.1605
Subject(s) - docosahexaenoic acid , placebo , eicosapentaenoic acid , dementia , medicine , fish oil , cognition , randomized controlled trial , placebo group , polyunsaturated fatty acid , psychiatry , fatty acid , fish <actinopterygii> , biology , biochemistry , disease , alternative medicine , pathology , fishery
primary care physicians and community organizations to provide comprehensive dementia care. Methods: Design: Pre-post evaluation one-year after program enrollment. Setting: Urban academic medical center with primarily fee-for-service reimbursement Participants: Community-dwelling adults enrolled in the program. Measurements: Caregivers completed the Cornell Scale for Depression in Dementia and the Neuropsychiatric Inventory Questionnaire (NPI-Q) about the patient; the Patient Health Questionnaire (PHQ-9) and Modified Caregiver Strain Index (MCSI) about themselves; and a survey assessing caregiver self-efficacy for managing dementia-related problems and accessing help developed for the ADC Program. Scales were compared using paired t-tests or Wilcoxon signed rank sum tests. Survey items were compared using McNemar’s test. Results: 240 patient-caregiver dyads were seen for an annual followup visit (57% of enrollees eligible), and 202 (84%) completed scales and surveys. Mean patient age was 82 years, 66% were female, and 64% lived with the caregiver. 65% of caregivers were female and 91% were spouses or children. Baseline scores for all scales, age, and gender did not differ between enrollees who completed a one-year follow-up visit and those who did not. One year after enrollment, patient cognitive and functional status had declined consistent with expected rates for dementia. For patients, caregivers reported fewer depressive symptoms (Cornell) and fewer behavioral symptoms (NPI-Q severity score). For themselves, caregivers reported fewer depressive symptoms (PHQ-9), less distress related to patients’ behaviors (NPI-Q distress score), and lower strain (MCSI). (Table) Conclusion: Although dementia co-management by a nurse practitioner does not alter the progression of dementia (cognitive and functional impairment), the UCLA ADC program was able to improve patient and caregiver outcomes associated with dementia. Higher self-efficacy for caregiving may result in improved behavioral management and increased support leading to less caregiver strain. Whether these improved clinical outcomes are associated with lower health care utilization remains to be determined.