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P3‐209: Cognitive functioning mediates the relationship between social functioning and activities of daily living in older adults
Author(s) -
Mewborn Catherine,
Lindbergh Cutter A.,
Dickens Jonathan M.,
Stapley Leslie,
Sharma Shubam,
Goldy Sean,
Bello Medina,
Renzi Lisa M.,
Hammond Billy R.,
Miller L. Stephen
Publication year - 2015
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2015.06.1581
Subject(s) - cognition , psychology , mediation , activities of daily living , social cognition , cognitive skill , social functioning , executive functions , developmental psychology , clinical psychology , psychiatry , distress , political science , law
Results: A cumulative cognitive quotient crossing one percentile interval line distinguished healthy controls from thosewho developed dementia with a sensitivity and specificity of 80%. Based on the 10year follow-up data, a sensitivity of 78% and specificity of 84%, positive predictive value was just over 50% (likely a reflection of the relatively weak diagnostic power of the MMSE), but negative predictive value was very high at 95%. Similar findings were noted for the 5-year follow data (sensitivity 80%, specificity 80%, positive predictive value 45%, negative predictive value 95%). Altogether, these results suggest that cognitive charts are highly efficient in identifying elderly individuals who are cognitively stable over time despite an overt decline in their scores on repeat MMSE. Conclusions: Similar to ‘growth charts’, we propose a method which factors in age and education to help determine whether elderly individuals show abnormal performance on serial MMSE. A significant decline on cognitive charts should prompt further investigation while a non-significant decline reliably identifies those individuals who do not need further cognitive work up.