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IC‐P‐103: Middle‐aged adults with subjective memory complaints: Clinical and brain structural features
Author(s) -
Rolandi Elena,
Cavedo Enrica,
Frisoni Giovanni Battista,
Galluzzi Samantha
Publication year - 2015
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2015.06.125
Subject(s) - voxel based morphometry , neuropsychology , voxel , middle frontal gyrus , episodic memory , medicine , psychology , effects of sleep deprivation on cognitive performance , cognition , audiology , analysis of variance , depressive symptoms , white matter , psychiatry , magnetic resonance imaging , radiology
hypometabolism in the fronto-temporal regions, parahippocampal gyrus and insula. Conclusions: The current findings indicate that severity of SMC is related to underlying alterations in specific regional cerebral glucose metabolism. The patterns of hyperand hypometabolism associated with increased SMC may reflect increased compensatory mechanisms of the posterior brain regions and decreased fronto-temporal functions in very early degenerative changes.