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The sensitivity to change over time of the Amsterdam IADL Questionnaire ©
Author(s) -
Koster Naomi,
Knol Dirk L.,
Uitdehaag Bernard M.J.,
Scheltens Philip,
Sikkes Sietske A.M.
Publication year - 2015
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2014.10.006
Subject(s) - activities of daily living , longitudinal study , dementia , gerontology , psychology , cognition , cognitive decline , cognitive skill , medicine , disease , psychiatry , pathology
This study aimed to investigate the sensitivity to change over time of a new informant‐based instrument to assess instrumental activities of daily living (IADL) during the course of dementia: the Amsterdam IADL Questionnaire © (A‐IADL‐Q). Methods Participants (n = 102) were patients and their informants who visited the Alzheimer Center of the VU University Medical Center. Linear mixed models with random effects were used to relate longitudinal change on the A‐IADL‐Q to diagnosis and to longitudinal change in cognitive measures. Results We found longitudinal change on the A‐IADL‐Q to differ between diagnosis ( P = .003), with dementia patients showing the fastest rate of decline ( P < .001). In addition, we found longitudinal change on the A‐IADL‐Q to be related to longitudinal change in cognitive measures (global cognition: P < .001; memory: P = .024; executive functioning: P = .028). Discussion Findings indicate the A‐IADL‐Q is sensitive to change over time in IADL functioning and can be used in evaluating treatment effects and assessing individual disease progress.