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P2‐236: FUNCTIONAL PERFORMANCE IN THE COMPLEX ACTIVITIES OF DAILY LIVING: CHANGE AND LOSS PROFILE IN A HEALTHY AGED POPULATION
Author(s) -
Labos Luisa Edith,
Trojanowski Sofia,
Del Rio Miriam,
Renato Alejandro
Publication year - 2014
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2014.05.913
Subject(s) - analysis of variance , activities of daily living , population , repeated measures design , medicine , gerontology , psychology , physical therapy , statistics , mathematics , environmental health
female and 78 male (age 72,31 Std 8,29 , instruction 8,6 Std 3.9) of which 104 have no cognitive pathology (control group); 49 subjects withMCI clinical diagnosis and 66 with mild/ moderate AD.The control group was evaluated with a General Cognitive Screening (Adas Cog) and MMSS. We established a cut point of 26 for the MMSS and normal performance in Adas Cog.An Anova analysis has been carried out considering the number of clusters, number of switching, number of exemplars and clusters size in the three groups.Results:The ANOVA analysis showed that: exemplars number, cluster and switching number are significant variables to identify the EA, MCI and Control groups. It was significant (Pr (>F) 1⁄4 .001) to distinguish between the means of the Control Group (8.23), MCI (5.18) and EA (3.64). It was also relevant the ANOVA of switchings (Pr (>F) 1⁄4 .001): Control Group (10.1), MCI (6.59) and EA (5.36). The cluster size distinguished the control group from MCI and EA , but not between them. Conclusions: The results obtained constitute a significant contribution to the knowledge of the normal and pathological lexical processing. The study of the clusters’organization in semantic fluency tasks might provide a new important marker in the clinical diagnosis profile of MCI patients.