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IC‐P‐183: EMPLOYING EARLY UPTAKE DATA FROM F18‐FLORBETAPIR SCANS AS AN ESTIMATE OF REGIONAL CEREBRAL BLOOD FLOW: COMPARISON TO F18‐FDG
Author(s) -
Devous Michael D.,
Joshi Abhinay D.,
Kennedy Ian,
Navitsky Michael,
Pontecorvo Michael J.,
Skovronsky Daniel J.,
Mintun Mark A.
Publication year - 2014
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2014.05.190
Subject(s) - cerebral blood flow , voxel , nuclear medicine , neuroimaging , medicine , standardized uptake value , correlation , concordance , positron emission tomography , radiology , pathology , psychology , mathematics , geometry , psychiatry
readers noted high gray matter signal relative to white matter, which made visual interpretation relatively straightforward.Exemplary negative and positive scans will be presented. The cognitive measures were evenly matched between the scan positive and negatives in the MCI population studied. Conclusions: [18 F]NAV4694 scans are easy to read with 100% agreement among the consensus readers. Baseline data indicates the scans are easy to read and cognitivemeasures among scan positive and negative subjects in this cohort were similarly matched. Sensitivity and specificity for conversion to AD is to be determined with data from the longer follow up.