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IC‐P‐164: GLUTAMATERGIC CONCENTRATION AS A BIOMARKER OF MEMORY PERFORMANCE IN AGING INDIVIDUALS
Author(s) -
Schoemaker Dorothee,
Near Jamie,
Gauthier Serge,
Pruessner Jens
Publication year - 2014
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2014.05.171
Subject(s) - glutamatergic , hippocampus , glutamate receptor , episodic memory , neuroscience , audiology , psychology , population , hippocampal formation , medicine , cognition , receptor , environmental health
in the anatomical region of interest (bilateral hippocampus).Results: Table 1 lists the results of the associations between each memory test score and bilateral hippocampal GM volume. The association between FCSRT scores with GM volume is greater than that of the CERAD scores with GM volume in the entire sample and also in the MCI/SCD subsample. Conclusions: Our results suggest that the FCSRT-scores predict hippocampal atrophy in AD and AD at-risk conditions better than the CERAD-scores. This supports the FCSRT as an instrument with greater sensitivity for hippocampal pathology than standard word list learning tests.