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P3‐265: INCREASED RELATIONSHIP BETWEEN MEDIAL TEMPORAL LOBE VOLUMES AND A NOVEL OBJECT‐LOCATION ASSOCIATION THAN A STANDARDIZED MEMORY TEST IN OLDER CONTROLS AND MILD COGNITIVE IMPAIRMENT
Author(s) -
Hampstead Benjamin,
Stringer Anthony,
Sathian K.
Publication year - 2014
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2014.05.1357
Subject(s) - psychology , recall , association (psychology) , temporal lobe , cognition , audiology , cognitive psychology , neuropsychology , neuroscience , medicine , epilepsy , psychotherapist
were between the left ACC and the right precentral gyrus and the left precuneus and bilateral middle occipital gyrus. Decreases were found between the left precuneus and parahippocampal gyrus. We also found correlations between FC and Stroop scores. Conclusions: The AD group showed more posterior DMN activity and the HC group showed more frontal activity preceding errors on the Stroop task, suggesting that the neural activity surrounding errors of SA differs between AD and HC. In AD, task related changes observed in the precuneus resulted in FC changes that correlated with poor performance on the Stroop task. These findings help identify neural correlates underlying SA deficits in AD.