Premium
P3‐159: EXECUTIVE DYSFUNCTION IN PREVALENT VERSUS INCIDENT AMNESTIC MILD COGNITIVE IMPAIRMENT
Author(s) -
Covell Gretchen Schlosser,
Caselli Richard J.
Publication year - 2014
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2014.05.1249
Subject(s) - neuropsychology , executive dysfunction , medicine , audiology , memory span , executive functions , cognition , cognitive impairment , psychology , cognitive decline , dementia , working memory , clinical psychology , disease , psychiatry
Background: Stroke is a leading cause of morbidity and is associated with motor and cognitive dysfunction. The aim of the study is toinvestigate whether, and to what extent, post-stroke walking performance at admission to a rehabilitation ward is associated with cognitive impairment. Methods: A retrospective study comprising 653 consecutive elderly ischemic stroke patients. Level of walking performance (WP) was determined by Functional Independence Measurement (FIMTM) sub-scale scores relevant to walking performance, where scores 5 points define low-walking performance (Low-WP) ability and scores >5 indicate high-walking performance (High-WP). Cognitive status was assessed by the Mini-Mental State Examination (MMSE), and scores lower than 24 points were considered as suggestive of cognitive impairment. Data was analyzed by t test, Chi-square test, multiple linear regression and logistic regression.Results:Age, gender, diabetes, atrial fibrillation and dementia emerged as the only statistically significant parameters differing between those with and without Low-WP. After adjustment for confounding variables, low-WP (odds ratio 2.86, 95% CI 1.01-8.1, p1⁄40.047) was associated with an increased risk of cognitive impairment. Conclusions: Lower walking performance in older ischemic stroke patients is significantly associated with cognitive decline.