O5‐02‐05: CORTICAL ATROPHY AND DEMYELINATION IN ALZHEIMER'S DISEASE AND IN TRAUMATIC BRAIN INJURY: A COMPARATIVE STUDY OF STRUCTURAL BRAIN CHANGES USING MULTIMODAL NEUROIMAGING | Zendy

Irimia Andrei | Zendy; Goh Matthew | Zendy; Torgerson Carinna M. | Zendy; Vespa Paul M. | Zendy; Horn John D. | Zendy

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O5‐02‐05: CORTICAL ATROPHY AND DEMYELINATION IN ALZHEIMER'S DISEASE AND IN TRAUMATIC BRAIN INJURY: A COMPARATIVE STUDY OF STRUCTURAL BRAIN CHANGES USING MULTIMODAL NEUROIMAGING

Author(s) -

Irimia Andrei,

Goh Matthew,

Torgerson Carinna M.,

Vespa Paul M.,

Horn John D.

Publication year - 2014

Publication title -

alzheimer's and dementia

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 6.713

H-Index - 118

eISSN - 1552-5279

pISSN - 1552-5260

DOI - 10.1016/j.jalz.2014.04.486

Subject(s) - atrophy , parahippocampal gyrus , traumatic brain injury , neuroimaging , psychology , neuroscience , medicine , superior temporal gyrus , population , gyrus , cerebral atrophy , pathology , temporal lobe , epilepsy , psychiatry , functional magnetic resonance imaging , environmental health

Microvascular lesions (7T MRI) Microinfarcts No. of MR scans 3 13 42 38 Presence 1 (33) 4 (31) 18 (43) 13 (34) No. 0 (0-1) 0 (0-1) 0 (0-5) 0 (0-2) Microbleeds No. of MR scans 5 12 40 36 Presence 0 (0) 5 (42) 12 (30) 19 (53) No. 0 (0-0) 0 (0-3) 0 (0-5) 1 (0-6) Other MRI markers (1.5/3T MRI) Lacunar infarcts (n1⁄4103) 0 (0) 0 (0) 9 (20) 12 (32) Large vessel infarcts (n1⁄4103) 0 (0) 1 (7) 2 (4) 0 (0) WMH volumes, mL (median (IQR)) (n1⁄494) 0.09 (0.01;2.14) 0.30 (0.09; 0.84) 1.15 (0.56; 4.35) 4.03 (0.95; 7.18)

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