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The prevalence of mild cognitive impairment and its etiological subtypes in elderly Chinese
Author(s) -
Jia Jianping,
Zhou Aihong,
Wei Cuibai,
Jia Xiangfei,
Wang Fen,
Li Fang,
Wu Xiaoguang,
Mok Vincent,
Gauthier Serge,
Tang Muni,
Chu Lan,
Zhou Youlong,
Zhou Chunkui,
Cui Yong,
Wang Qi,
Wang Weishan,
Yin Peng,
Hu Nan,
Zuo Xiumei,
Song Haiqing,
Qin Wei,
Wu Liyong,
Li Dan,
Jia Longfei,
Song Juexian,
Han Ying,
Xing Yi,
Yang Peijie,
Li Yuemei,
Qiao Yuchen,
Tang Yi,
Lv Jihui,
Dong Xiumin
Publication year - 2014
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2013.09.008
Subject(s) - medicine , confidence interval , dementia , cognitive impairment , etiology , gerontology , disease , pediatrics
Background Epidemiologic studies on mild cognitive impairment (MCI) are limited in China. Methods Using a multistage cluster sampling design, a total of 10,276 community residents (6096 urban, 4180 rural) aged 65 years or older were evaluated and diagnosed with normal cognition, MCI, or dementia. MCI was further categorized by imaging into MCI caused by prodromal Alzheimer's disease (MCI‐A), MCI resulting from cerebrovascular disease (MCI‐CVD), MCI with vascular risk factors (MCI‐VRF), and MCI caused by other diseases (MCI‐O). Results The prevalences of overall MCI, MCI‐A, MCI‐CVD, MCI‐VRF, and MCI‐O were 20.8% (95% confidence interval [CI] = 20.0–21.6%), 6.1% (95% CI = 5.7–6.6%), 3.8% (95% CI = 3.4–4.2%), 4.9% (95% CI = 4.5–5.4%), and 5.9% (95% CI = 5.5–6.4%) respectively. The rural population had a higher prevalence of overall MCI (23.4% vs 16.8%, P < .001). Conclusions The prevalence of MCI in elderly Chinese is higher in rural than in urban areas. Vascular‐related MCI (MCI‐CVD and MCI‐VRF) was most common.