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P4–361: The influence of mild cognitive impairment on measures of fall risk in community‐dwelling older adults
Author(s) -
Blackwood Jennifer,
Shubert Tiffany,
Chase Carla,
Fogarty Kieran
Publication year - 2013
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2013.08.195
Subject(s) - fear of falling , montreal cognitive assessment , falling (accident) , cognition , timed up and go test , balance (ability) , medicine , gait , cognitive impairment , cognitive decline , falls in older adults , confidence interval , risk assessment , gerontology , poison control , physical medicine and rehabilitation , psychology , injury prevention , dementia , disease , psychiatry , medical emergency , computer security , computer science
The link between ET and PD has frequently been debated in the literature and such patients developing PD after ET are named ETPD, however, the development of dementia has not been described in patients with ETPD. In this study, we have described a clinical case series of 17 patients with initially diagnosed as ET, who developed parkinsonism and subsequent development of dementia. We named this combination of ET, PD and dementia as ETPDD and in these patients, using clinical presentation and FDG-PET studies, the similarities and differences to Parkinson Disease Dementia and other dementia are described. Methods: All patients underwent a detailed neurologic history and examination by samemovement disorders specialist. Medical informations of patients were obtained from the patients and family members to clarify the relationship between these disorders. The patient’s global cognitive status and severity of dementia were assessed with MMSE and CDR. Demographic and historical data including age, sex, age at tremor onset, duration of postural tremor, type of tremor, age at parkinsonism and dementia onset, the time between ETand PD and PD and dementia, family history of PD, ET, other movement disorders and dementia, and similarities and differences to other dementia were recorded. The diagnosis of PD was established according to the UK-PD Society Brain Bank criteria and the criteria for dementia from DSM-IV was applied. Results: RESULTS Patients who met the following criteria were classified as having ETPDD. (1) presence of both postural-action hand tremor as first symptom on their medical history. (2) symptoms of postural-action tremor for at least 3 to 5 years prior to the onset of other signs of PD.(3) cognitive dysfunctions, impaired activities of daily living and measured by MMSE. Conclusions: Present study specifically focused on the similarities and differences to PD dementia and other dementia, including clinical presentation and FDG-PET studies, leading clinicians to suspect a link among them. To our knowledge, this is the first case series to describe the coincidental occurrence of these three disorders in a single patient.