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P4‐275: High prevalence of nocturnal hypoxia in a dementia cohort
Author(s) -
Clionsky Emily,
Clionsky Mitchell
Publication year - 2012
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2013.08.056
Subject(s) - dementia , medicine , pulse oximetry , hypoxia (environmental) , cohort , neurocognitive , pediatrics , cardiology , anesthesia , cognition , psychiatry , chemistry , disease , organic chemistry , oxygen
longitudinal comparisons of subcortical structural volume for 3 years, the EOAD group showed more rapid volumetric decline in the bilateral caudate, bilateral putamen, and left thalamus than the LOAD group. Conclusions: Our longitudinal study suggests that the rate of decline in subcortical structure observed in the EOAD group appeared more rapid and extensive than in the LOAD group. LOAD only showed rapid volumetric decline in hippocampus, therefore cognitive impairment more focused on memory. In contrast, EOAD showed more rapid volumetric decline in caudate, putamen, and thalamus, therefore cognitive impairment revealed on diverse cognitive domain.