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P4‐261: How are pain responses altered by severe Alzheimer's disease?
Author(s) -
Beach Paul,
Miranda Melodie,
Bozoki Andrea
Publication year - 2012
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2013.08.042
Subject(s) - analysis of variance , threshold of pain , post hoc analysis , dementia , medicine , cold pressor test , psychology , stimulus (psychology) , analgesic , disease , audiology , heart rate , anesthesia , blood pressure , psychotherapist
based sample of 1,563 elderly subjects aged 60 years or older was performed. Instruments applied: Fuld Object Memory Evaluation (FOME), Mini Mental Status Examination (MMSE), the Informant Questionnaire on Cognitive Decline in the Elderly (IQCODE), the Bayer Activities of Daily Living Scale (B-ADL), Cambridge Mental Disorders of the Elderly Examination (CAMDEX), and a socio-economic questionnaire. Based on a pilot study, these instruments were combined to classify subjects with CFI. Results: The overall prevalence of CFI was 16% (95% CI; 7.519.6%). The univariate analysis indicated independent factors associated to CFI. After adjusting for all the variables, the multivariate analysis showed an association with the age group 75-79 (OR1⁄414.0; p<0.001); no physical activity (OR1⁄41.5; p1⁄40.014); not going to the museum (OR1⁄43.8; p<0.001), not watching TV (OR1⁄42.4; p1⁄40.003); not reading journals (OR1⁄41.7; p1⁄40.006), and not reading books (OR1⁄41.8; p1⁄40.002). There was no association with gender, socioeconomic class, marital status and educational level. Conclusions: In our sample, going to the museum, reading books, journals and watching TV seem to protect from CFI. Regarding the lack of association between educational level and CFI, some studies have found that leisure activities could be a proxy of education. There was a great influence of physical activity on the prevalence of CFI. These findings reinforce the importance of developing programs of leisure activities in order to enhance the cognition and general health in elderly people.