Premium
P2–274: Predictors of activities of daily living in older adults: The Frontal Systems Behavior Scale (FrSBe) and neuropsychological test performance
Author(s) -
Deutsch Gayle,
Fine Eric,
Tan Simon,
Llanes Seoni,
Karzmark Peter,
Fenesy Michelle,
Hantke Nathan,
Zeifert Penelope,
Kerchner Geoffrey
Publication year - 2013
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2013.05.921
Subject(s) - psychology , neuropsychology , dementia , executive functions , trail making test , neuropsychological test , wisconsin card sorting test , boston naming test , verbal fluency test , wechsler adult intelligence scale , clinical dementia rating , cognition , test (biology) , clinical psychology , gerontology , developmental psychology , psychiatry , disease , cognitive impairment , medicine , paleontology , biology
famous name and face retrieval in relation to performance on the FCSRT and to PiB retention (DVR, cerebellar reference) as a continuous variable in the precuneus, co-varying for age. Results: Retrieval of famous names (t(24)1⁄41.14, p 1⁄4 .267) and occupations (t(24)1⁄41.55, p 1⁄4 .135) was equivalent for MCI and CN subjects. Across the entire sample, retrieval of the names of famous individuals was positively related to both free recall (r1⁄4.723, p1⁄4.001) and cued recall on the FCSRT (r1⁄4.629, p1⁄4.003). Similarly, retrieval of occupations of famous individuals was positively related to free recall (r1⁄4.579, p1⁄4.007) and cued recall (r1⁄4.566, p1⁄4.009) on the FCSRT. Within the PiB-PET subgroup, increasing Abeta deposition was related to worse performance retrieving occupations (r1⁄4.555, p1⁄40.01) with a trend for retrieving famous names (r1⁄4.366, p1⁄4.074). Conclusions: Results suggest that semantic memory decline co-occurs with episodic memory decline and is furthermore associated with underlying Alzheimer’s pathology. Semantic memory decline may be a useful early marker in MCI and preclinical AD.