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P2–233: Assessment of cerebral vasoreactivity using ultrasound techniques in Alzheimer's disease
Author(s) -
Giubilei Franco,
Cipollini Virginia,
Sette Giuliano,
De Carolis Antonella,
Capone Francesca Tari,
Bianchi Valentina,
Monti Micaela Sepe
Publication year - 2013
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2013.05.879
Subject(s) - medicine , cardiology , transcranial doppler , dementia , cerebral blood flow , correlation , pathological , resting state fmri , disease , radiology , geometry , mathematics
205 cases (27.5%; 99 arteriolosclerosis, 65 infarcts and 41 cases both). Multivariate analysis using logistic regression showed that cerebrovascular disease was more frequent in individual with higher age (p1⁄40.011; Exp (B)1⁄4 1.561; 95% CI 1.106-2.202), less years of schooling (p1⁄40.035; Exp (B) 1⁄4 0.690; 95% CI 0.488-0.975) and lower SES (p1⁄40.034; Exp (B)1⁄4 0.662; 95% CI 0.453-0.969). Conclusions: Higher prevalence of dementia in low educated individuals may be not only due to low cognitive reserve, but also to the increased burden of cerebrovascular disease.