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P2–160: Automated diagnosis of Alzheimer's disease using multimodal analysis of surface‐based FDG‐uptake and cortical thickness
Author(s) -
Yun Hyuk Jin,
Lee JongMin
Publication year - 2013
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2013.05.805
Subject(s) - neuroimaging , support vector machine , receiver operating characteristic , artificial intelligence , pattern recognition (psychology) , dementia , segmentation , computer science , atrophy , pathology , medicine , neuroscience , disease , machine learning , psychology
gulate cortex (PCC) and medial temporal lobe (MTL) in cognitively normal individuals with abnormal levels of cerebrospinal fluid (CSF) Ab42 or ptau181 A: PCC functional connectivity compared between CSF Ab42 negative vs. CSF Ab42 positive; B: PCC functional connectivity compared between CSF ptau181 negative vs. CSFptau181 positive; C: MTL functional connectivity compared between CSF Ab42 negative vs. CSFAb42 positive;D: MTL functional connectivity maps were compared using random effects analyses. Maps display random effects decreases in correlations (hot color) and each comparisons (cold color) in each comparisons.Mapswere thresholded at a voxel-level [Z]> 2.5 and cluster size> 35 voxels, uncorrected for multiple comparisons.