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P2–116: Cognitive impairment in moderate chronic kidney disease: The brain in kidney disease (BRINK) study
Author(s) -
Stendahl John,
Heubner Brooke,
Tupper David,
Pederson Sarah,
Amiot Elizabeth,
Kenigsberg Tat'Yana,
Murray Anne
Publication year - 2013
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2013.05.760
Subject(s) - medicine , kidney disease , verbal memory , trail making test , executive dysfunction , cognition , neuropsychology , visual memory , dialysis , stroke (engine) , verbal learning , cognitive test , diabetes mellitus , neuropsychological test , audiology , psychiatry , endocrinology , mechanical engineering , engineering
negative in a nonfluent and two semantic impaired patients. Ab42 in CSF were inversely correlated with total tau and positively with PIB PET. Conclusions: There were differences of cortical atrophy patterns among the three subgroups and of anatomic correlates according to specific clinical symptoms like initial presenting symptoms, repetition failure, and prosopagnosia. PIB-PET had reflected amyloid burden in Korean PPA patients too. Based on the findings with clinical features, voxel-based analysis of SPGR MRI, PIB-PET and CSF biomarkers, logopenic subgroup might had some common pathology of Alzheimer’s disease.