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P2–091: Mild cognitive impairment subtypes: An MEG study
Author(s) -
Cabranes Jose Antonio,
Garcia Maria Eugenia,
Cuesta Pablo,
Castellanos Nazareth,
Garcés Pilar,
Aurtenexte Sara,
Bajo Ricardo,
Delgado Maria Luisa,
Montejo Pedro,
Marcos Alberto,
Barabash Ana,
Maestú Fernando,
Fernández Alberto
Publication year - 2013
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2013.05.734
Subject(s) - cognitive impairment , audiology , dementia , magnetoencephalography , cognition , neurophysiology , psychology , medicine , neuroscience , electroencephalography , disease
Previous studies of the dementia continuum have characterized the early disruption of the brain oscillatory activity at the stage of Mild cognitive impairment (MCI). Reduction in power in posterior regions in the alpha band has been one of the landmarks of the Alzheimer Disease accompanied by the anteriorization of the theta band power. However, little is known about the neurophysiological differences between single and multidomain MCI patients.Our goal is to study the differences in oscillatory magnetic activity between amnestic single and multidomain MCI. This will allow us to test whether the effect of the impairment in a single cognitive domain or in a more widespread functional impairment can be reflected in specific neurophysiological profiles