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P1–311: Comparison of automated segmentation of intracranial volume between 3D T1 and 3D T2 sequences
Author(s) -
Bracoud Luc,
Goutttard Sylvain,
Schaerer Joël,
Pueyo Maria,
Bonneville Fabrice,
Roche Florent,
Istace Audrey,
Yu HuiJing,
Pachai Chahin,
Vellas Bruno
Publication year - 2013
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2013.05.537
Subject(s) - brain size , segmentation , context (archaeology) , multivariate statistics , volume (thermodynamics) , computer science , medicine , artificial intelligence , magnetic resonance imaging , radiology , machine learning , biology , paleontology , physics , quantum mechanics
shows parametric maps of CTTH from one AD patient and one control. Conclusions:We found elevated CTTH in mild to moderate AD, consistent with the prediction that capillary dysfunction plays a role in the etiopathogenesis of AD. Studies should examine the value of perfusion MRI based CTTH estimates in the early detection of AD and other dementias, and as a tool to study capillary dysfunction in AD risk factors.