Premium
P4–221: Characterizing the effect of Alzheimer's disease on everyday motion behavior
Author(s) -
Dyrba Martin,
Koldrack Philipp,
Schubert Susanne,
Bauer Alexandra,
Kirste Thomas,
Teipel Stefan
Publication year - 2013
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2013.05.1613
Subject(s) - principal component analysis , artificial intelligence , dyad , psychology , rating scale , classifier (uml) , random forest , computer science , rhythm , physical medicine and rehabilitation , pattern recognition (psychology) , developmental psychology , medicine
and impaired comprehension (concrete/abstract inversion); insight decreased (even in nonverbal tasks); syntax intact and absence of phonological errors; presence of semantic paraphasias and poor category fluency, and surface dyslexia. Neurological examination was normal. A brain MRI showed a left hyppocampal and fronto-temporal atrophy and the SPECT showed bilateral fronto-temporal hypometabolism.Conclusions:We identified a characteristic patientwith semantic dementia shownas a progressive deterioration of semantic knowledge associated with focal, typically asymmetric temporal lobe degeneration. But, it’s very uncommon to find an asymmetric hippocampal atrophy with intact autobiographical memory. There are some studies showing that maybe right frontal lobe could equalize this deficit.