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P4–111: Predicting driving safety in people with dementia
Author(s) -
Yaari Roy,
Ayutyat Napatkamon,
Fleisher Adam,
Brand Helle,
Burke Anna,
Tariot Pierre
Publication year - 2013
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2013.05.1501
Subject(s) - exact test , analysis of variance , test (biology) , univariate analysis , dementia , psychology , medicine , multivariate analysis , paleontology , disease , biology
longitudinal study of community-dwelling PwAD was performed between April 2009 and March 2012 encompassing a baseline and a 2.5-year follow-up. We focused on new GL events and the associated factors from their demographic data, cognitive functions by CASI and MMSE, and daily navigational abilities by the Questionnaire of Everyday Navigational Ability (QuENA). The study population consisted of 185 PwAD and their co-habitant collaterals. At the baseline, 95 had experienced GL (Group B), while and the remaining 90 (Group A) had not. Results: After a 2.5-year period, 33.3% inGroupA developedGL (incidence) and 40% inGroupB developed GL (recurrence). Multiple logistic regression analysis revealed that inattention on the QuENA and orientation on the CASI had independent effects on the incidence, while younger age and the absence of a safety range spelled danger for recurrence. The nature of incidence and recurrence of GL in these AD patients was quite different. During the 2.5 years, PwAD with GL incidence deterioratedmore inmentalmanipulation onCASI than thosewithout. Conclusions: CASI and the QuENA can indicate risk of GL incidence. We suggest that once GL occurs, the collaterals of PwAD must take the responsibility to prevent it from recurring, especially for younger patients. In addition, GL may be a behavioral manifestation for subtypes of AD.