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P4–071: Spectrum of NOTCH3 mutations in Korean patients with clinically suspicious cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy
Author(s) -
Yoon Cindy,
Kim YoungEun,
Seo Sang Won,
Ki ChangSeok,
Na Duk L.,
Kim JongWon
Publication year - 2013
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2013.05.1460
Subject(s) - cadasil , leukoencephalopathy , exon , sanger sequencing , mutation , genetics , medicine , pathology , biology , gene , disease
Age (years) 69.165.4 72.866.3 74.166.9 Sex (male/female) 38/62 88/203 54/150 Education (years) 9.565.1 8.265.1 8.065.1 Body mass index (kg/m) 4.262.4 24.163.4 23.163.6 Total cholesterol (mmol/L) 82.9632.2 83.7637.3 80.4637.5 LDL-cholesterol (mmol/L) 58.2646.4 64.9648.4 71.0651.6 Triglyceride (mmol/L) 111.8680.6 101.6674.4 108.4676.8 Current smoking (+/-) 6/94 17/274 9/195 Habitual alcohol intake (+/-) 36/64 76/215 44/160 Presence of cardiovascular disease (+/-) 4/96 37/254 9/195 Presence of hypertension (+/-) 52/48 147/144 92/112 Presence of diabetes mellitus (+/-) 18/82 65/226 38/165 Systolic blood pressure (mmHg) 133.0620.1 138.2618.9 135.1619.2 Ankle brachia index 1.2760.2 1.1660.2 1.1760.18