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P3–263: Preliminary evaluation of a multicomponent cognitive intervention program for people with amnestic mild cognitive impairment and their family partners
Author(s) -
Lee Kyoungmin,
Lee Dong Young,
Sohn Bo Kyung,
Choe Young Min,
Woo Jong Inn
Publication year - 2013
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2013.05.1337
Subject(s) - psychosocial , mood , intervention (counseling) , cognition , quality of life (healthcare) , clinical psychology , caregiver burden , psychology , activities of daily living , medicine , dementia , psychiatry , disease , psychotherapist
Methods: To date, 137 participants were randomized into an online-only (n1⁄446), online+face-to-face (n1⁄445), or an active control group (n1⁄446). Participants underwent a comprehensive baseline evaluation prior to randomization which included the assessment of AD risk profile with our validated ANU-Alzheimer’s disease risk index (ANU-ADRI, Anstey et al. 2013), as well as a psychological, cognitive, and physical examination, and optional blood tests. Participants were evaluated again immediately following the 12-week intervention, and 3 months later. Results: Selected sample characteristics are listed in Table 1. Overall, 132 participants (96.4%) had at least two risk factors and/or fewer than two protective factors. The most prevalent risk factor (66.2%) was overweight or obese BMI and the least prevalent protective factor (39%) was cognitive activity. The sample was in the healthy range on all cognitive measures. No differences between the three groups were observed on any of the demographic, lifestyle, medical or cognitive measures. Conclusions: Baseline data confirms that the sample is cognitively healthy, and that it has on average three AD-risk factors. Successful randomization was demonstrated by showing that no group differences existed on any of the baseline characteristics that may influence outcomes. Final follow up data are expected by September 2013 and will show whether the intervention is associated with a reduced AD-risk profile. If successful, the findings will contribute to the development of further dementia risk reduction interventions.Long term follow-up studies are required to examine whether reduction in exposure to dementia risk factors will be associated with reduced prevalence.