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P3–210: Self‐reported quality of life after retirement and cognitive function: Data from the Nurses' Health Study
Author(s) -
Kang Jae,
Grodstein Francine
Publication year - 2013
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2013.05.1283
Subject(s) - medicine , cognition , health and retirement study , gerontology , quality of life (healthcare) , cohort , depression (economics) , confounding , telephone interview , population , demography , psychology , psychiatry , environmental health , social science , nursing , pathology , sociology , economics , macroeconomics
analyses were performed in which the volume of white matter hyperintensities (WMH) was used as the dependent variable.Results: In women, brain atrophy at an average age of 75.7 was negatively associated with both minutes of walking (p1⁄40.02) and the mean number of grams of fish consumed (p1⁄40.04) at age 50. No association of walking and fish consumption with brain atrophy was evident in men. In both men and women, increased age was associated with greater brain atrophy. Neither walking nor fish consumption was associated with WMH volume. Conclusions: The findings are consistent with previous studies showing that consumption of foods containing high amounts of omega 3 fatty acids as well as increased physical exercise are associated with reduction in brain atrophy with age. The fact that this association was only evident in women may be related to the interaction of female gender with exercise (Eur J Neurosci 2001;14(12): 1992-2002) and omega 3 fatty acids (Aging Res Rev 2011;10: 124-131) in the upregulation of BDNF.