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P3–178: Results from the Israel Diabetes and Cognitive Decline Study: Genes and glycemic control
Author(s) -
Beeri Michal Schnaider,
RavonaSpringer Ramit,
Moshier Erin,
Schmeidler James,
Godbold James,
Preiss Rachel,
Koifmann Keren,
Hofmann Hadas,
Heymann Anthony
Publication year - 2013
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2013.05.1250
Subject(s) - dementia , diabetes mellitus , glycemic , cognition , type 2 diabetes , medicine , cognitive decline , gerontology , episodic memory , psychology , psychiatry , disease , endocrinology
with a proportion of 7.97% (p-value <0.0001) within our study population. Simulation study also shows that failure to account for this immune subgroup may result in bias in survival estimates and errors in identifying risk factors. Conclusions: Our study suggests that some subjects are immune to dementia. This subgroup of immune individuals should be adjusted for in any survival analysis to produce correct estimates for the probability of the age of onset of dementia and to identify correct risk factors for the age of onset of dementia.