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P3–164: Anemia and risk of dementia in older biracial adults: Findings from the Health ABC study
Author(s) -
Hong Chang Hyung,
Falvey Cherie,
Harris Tamara,
Simonsick Eleanor,
Satterfield Suzanne,
Ferrucci Luigi,
Metti Andrea,
Patel Kushang,
Yaffe Kristine
Publication year - 2013
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2013.05.1236
Subject(s) - dementia , anemia , medicine , hazard ratio , proportional hazards model , red blood cell distribution width , mean corpuscular volume , gerontology , confidence interval , hematocrit , disease
higher intake of potassium (MCI:RR 1.16, 95%CI 1.15-2.28, p1⁄40.002; MCD:RR 1.06, 95%CI 0.99-1.13, p1⁄4.085) and phosphorous (MCI:RR 1.62, 95%CI 1.15-2.28, p1⁄40.006; MCD:RR 1.15, 95%CI 1.010.31, p1⁄40.033). Relative risk based on 100mg increments. Conclusions: In young old individuals living in the community higher dietary intake of calcium and magnesium was associated with a decreased risk of MCI/ MCD while higher intake of potassium and phosphorous was associated with an increased risk. These results suggest that dietary intake of minerals known to be implicated in biological processes associated with vascular and Alzheimer’s pathology may contribute to disease progression and require further attention.