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IC‐P‐112: The pattern of cerebral hypometabolism and its association with clinical ratings in cognitively normal older adults with and without significant fibrillar amyloid burden: Findings from the Alzheimer's Disease Neuroimaging Initiative
Author(s) -
Protas Hillary,
Chen Kewei,
Reschke Cole,
Roontiva Auttawut,
Liu Xiaofen,
Parks Stephanie,
Lee Wendy,
Bauer Robert,
Ayutyat Napatkamon,
Thiyyagura Pradeep,
Koeppe Robert,
Jagust William,
Foster Norman,
Weiner Michael,
Fleisher Adam,
Reiman Eric
Publication year - 2013
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2013.05.109
Subject(s) - neuroimaging , posterior cingulate , pittsburgh compound b , voxel , alzheimer's disease neuroimaging initiative , psychology , disease , medicine , association (psychology) , alzheimer's disease , audiology , pathology , neuroscience , cognition , radiology , psychotherapist
Figure 1. Voxel-wise analyses assessing functional connectivity of the posterior cingulate cortex (PCC) and medial temporal lobe (MTL) in cognitively normal individuals with abnormal levels of cerebrospinal fluid (CSF) Ab42 or ptau181 A: PCC functional connectivity compared between Hillary Protas, Kewei Chen, Cole Reschke, Auttawut Roontiva, Xiaofen Liu, Stephanie Parks, Wendy Lee, Robert Bauer, III, Napatkamon Ayutyanont, Pradeep Thiyyagura, Robert Koeppe, William Jagust, Norman Foster, Michael Weiner, Adam Fleisher, Eric Reiman ALZHEIMER’S DISEASE NEUROIMAGING INITIATIVE (ADNI), Banner Alzheimer’s Institute, Phoenix, Arizona, United States; Banner Alzheimer’s Institute; Arizona Alzheimer’s Consortium, Phoenix, Arizona, United States; University of Michigan, Ann Arbor, Michigan, United States; University of California, Berkeley, Berkeley, California, United States; University of Utah, Salt Lake City, Utah, United States; University of California San Francisco, San Francisco, Utah, United States; University of California, San Diego, San Diego, California, United States. Contact e-mail: hillary.protas@bannerhealth.com