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P2–373: Exercise is effective in preventing high‐fat‐diet–induced beta‐amyloid deposition and memory deficit but continuation is necessary to keep the effect of exercise in APP transgenic mice
Author(s) -
Maesako Masato,
Uemura Kengo,
Kubota Masakazu,
Kinoshita Ayae
Publication year - 2013
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2013.05.1022
Subject(s) - neprilysin , medicine , endocrinology , genetically modified mouse , amyloid beta , physical exercise , disease , transgene , chemistry , enzyme , biochemistry , gene
rehabilitation, cognitive stimulation, cognitive training), 5 to caregivers intervention (two for managing behavioral symptoms and reducing caregiver burden), 2 to functional training (ADL) and 2 to physical exercise. The main population studied, was of elderly individuals with Alzheimer’s disease and mild cognitive impairment. Conclusions: This first review gives us a preliminary sight of the ongoing national production on NPIs directed to patients with dementia in Brazil. Most studies it was Multicomponent Interventions. None of the studies retrieved investigated the cost effectiveness of the intervention strategies. More extensive studies are needed for analyzing the methodologies and variables used, as well as classifying the evidence level of the published studies. This will contribute to future consensus and recommendations for the clinical practice in Brazil.