Premium
IC‐P‐078: Dissociating volume and intensity differences in familial Alzheimer's disease
Author(s) -
Cash David,
Ridgway Gerard,
Modat Marc,
Ryan Natalie,
Kinnunen Kirsi,
Cardoso Manuel,
Benzinger Tammie,
Jack Clifford,
Raichle Marc,
Marcus Daniel,
Ringman John,
Thompson Paul,
Ghetti Bernardino,
Salloway Stephen,
Sperling Reisa,
Schofield Peter,
Masters Colin,
Martins Ralph,
Mayeux Richard,
Weiner Michael,
Bateman Randall,
Fagan Anne,
Goate Alison,
Buckles Virginia,
Moulder Krista,
Morris John,
Rossor Martin,
Ourselin Sebastien,
Fox Nick
Publication year - 2013
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2013.05.075
Subject(s) - precuneus , grey matter , temporal lobe , voxel , intensity (physics) , white matter , posterior cingulate , middle frontal gyrus , fornix , psychology , nuclear medicine , hippocampus , neuroscience , magnetic resonance imaging , medicine , cognition , radiology , physics , quantum mechanics , epilepsy
Figure. Grey matter volume differences between (row 1) Control and FAD (row 2) Control and SAD, displayed at p < 0.05 FWE corrected using threshold free cluster enhancement. In the third row, the two atrophy patterns are overlaid to indicate areas of overlap in both groups (green areas). The bottom row provides percentage effect maps of a direct comparison between the SAD and FAD groups, with blue indicating areas where there is less GM in the FAD subjects and red/yellow indicating the areas where there is less GM in the SAD subjects.