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O5–05–03: Vitamin D and incident dementia in the Cardiovascular Health Cognition Study
Author(s) -
Soni Maya,
Lang Iain,
Langa Kenneth,
Chavez Paolo,
Annweiler Cedric,
Fried Linda,
Kestenbaum Bryan,
Lopez Oscar,
Llewellyn David
Publication year - 2013
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2013.04.495
Subject(s) - dementia , medicine , hazard ratio , vitamin d and neurology , population , body mass index , proportional hazards model , prospective cohort study , cognitive decline , disease , confidence interval , environmental health
risk of dementia; OR in a multivariate logistic regression was 2.91 (95% CI 1.37-6.16). More social contact at baselinewas associated with lower risk of incident dementia; OR in the multivariate analysis was 0.87 (95% CI 0.78-0.97). Therewere no significant associations between vascular risk factors or comorbidities and dementia risk. Conclusions: Presence of depression at baseline seems to be associated with higher risk of incident dementia after 5 years, whereas more frequent social contacts seem to be associated with lower risk. This highlights the possible role of psychosocial factors in dementia development among the oldest old. Further research on risk and protective factors is needed for these age groups.